IRF5 抗体 (AA 176-240)
Quick Overview for IRF5 抗体 (AA 176-240) (ABIN121152)
抗原
See all IRF5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 176-240
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特异性
- The antibody recognizes Human and Mouse Interferon Regulatory Factor 5 (IRF-5). Other species not tested.
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纯化方法
- Protein-G affinity chromatography
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免疫原
- Recombinant human IRF-5 (176-240 aa) purified from E. coli
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亚型
- IgG1
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应用备注
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ELISA. Western blot (1/500 - 1/1,000). Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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: "Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients. ..." in: Frontiers in immunology, Vol. 10, pp. 1029, (2019) (PubMed).
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: "Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients. ..." in: Frontiers in immunology, Vol. 10, pp. 1029, (2019) (PubMed).
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- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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别名
- IRF5
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背景
- IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.Synonyms: IRF-5, Interferon regulatory factor 5
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基因ID
- 3663
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UniProt
- Q13568
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途径
- TLR signaling, Autophagy
抗原
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