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IRF5 抗体 (AA 176-240)

This anti-IRF5 antibody is a 小鼠 单克隆 antibody detecting IRF5 in WB, IP, IHC (p) 和 EIA. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN121152
发货至: 中国

Quick Overview for IRF5 抗体 (AA 176-240) (ABIN121152)

抗原

See all IRF5 抗体
IRF5 (Interferon Regulatory Factor 5 (IRF5))

适用

  • 69
  • 38
  • 22
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
人, 小鼠

宿主

  • 67
  • 11
  • 1
  • 1
小鼠

克隆类型

  • 58
  • 22
单克隆

标记

  • 58
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This IRF5 antibody is un-conjugated

应用范围

  • 55
  • 32
  • 21
  • 16
  • 14
  • 12
  • 9
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

10T1
  • 抗原表位

    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 176-240

    特异性

    The antibody recognizes Human and Mouse Interferon Regulatory Factor 5 (IRF-5). Other species not tested.

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human IRF-5 (176-240 aa) purified from E. coli

    亚型

    IgG1
  • 应用备注

    ELISA. Western blot (1/500 - 1/1,000). Immunoprecipitation. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.09 % Sodium Azide

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • Idborg, Zandian, Ossipova, Wigren, Preger, Mobarrez, Checa, Sohrabian, Pucholt, Sandling, Fernandes-Cerqueira, Rönnelid, Oke, Grosso, Kvarnström, Larsson, Wheelock, Syvänen, Rönnblom, Kultima et al.: "Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients. ..." in: Frontiers in immunology, Vol. 10, pp. 1029, (2019) (PubMed).

  • 抗原

    IRF5 (Interferon Regulatory Factor 5 (IRF5))

    别名

    IRF5

    背景

    IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.Synonyms: IRF-5, Interferon regulatory factor 5

    基因ID

    3663

    UniProt

    Q13568

    途径

    TLR signaling, Autophagy
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