Integrin beta 2 抗体 (FITC)
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Quick Overview for Integrin beta 2 抗体 (FITC) (ABIN120699)
抗原
See all Integrin beta 2 (ITGB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (Integrin beta2 chain).
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免疫原
- Leucocytes of a patient suffering from a LGL-type leukaemia
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亚型
- IgG1
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anti-Integrin beta 2 (ITGB2) antibody
ITGB2 适用: 人 FACS, WB, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 适用: 人 FACS, WB, IP, Func, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 70-170) antibodyITGB2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) antibody (Biotin)ITGB2 适用: 人 FACS, WB, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal MEM-48 Biotin
anti-Integrin beta 2 (ITGB2) antibody (FITC)ITGB2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-48 FITC
anti-Integrin beta 2 (ITGB2) antibody (PE)ITGB2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-48 PE
anti-Integrin beta 2 (ITGB2) antibodyITGB2 适用: 小鼠 FACS, WB, IP, Func, IHC (fro), IHC (p) 宿主: 大鼠 Monoclonal M18-2 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 559-700) antibodyITGB2 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3C11G5 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 17-382) antibodyITGB2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) (AA 701-770) antibodyITGB2 适用: 人, 大鼠 ELISA, IHC (fro), ICC, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- Integrin beta 2 (ITGB2)
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别名
- CD18 / ITGB2
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背景
- CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. CD18, integrin b2 subunit, forms heterodimers with four types of CD11 Molecule to constitute leukocyte (b2) integrins: aLb2 (CD11a/CD18, LFA-1), aMb2 (CD11b/CD18, Mac-1, CR3), aXb2 (CD11c/CD18) and aDb2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits. These integrins are essential for proper leukocyte migration, mediating intercellular contacts. Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease. CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
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基因ID
- 3689
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UniProt
- P05107
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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