CD59 抗体
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北京 101111
Quick Overview for CD59 抗体 (ABIN120694)
抗原
See all CD59 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody MEM-129 reacts with CD59 (Protectin).
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纯化方法
- Thiophilic Adsorption-Affinity Chromatography and Size-Exclusion Chromatography.
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纯度
- > 95 % (by SDS-PAGE).
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免疫原
- Human peripheral blood lymphocytes
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亚型
- IgM
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应用备注
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Flow Cytometry. Functional Studies (The antibody activates T-cells).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- CD59
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别名
- CD59
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背景
- CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
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基因ID
- 966
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UniProt
- P13987
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途径
- Complement System
抗原
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