CD42b 抗体
-
- 抗原 See all CD42b (GP1BA) 抗体
- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
-
适用
- 人, 灵长类
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD42b antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 纯化方法
- Protein A Chromatography
- 免疫原
- Peripheral blood mononuclear cells of a patient suffering with CLL
- 克隆位点
- HIP1
- 亚型
- IgG1
- Top Product
- Discover our top product GP1BA Primary Antibody
-
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibody
GP1BA 适用: 人 WB, FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6H6H10 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibodyGP1BA 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6H6B11 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-291) antibodyGP1BA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-128) antibodyGP1BA 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 WB, FACS, ELISA, IP, ICC 宿主: 小鼠 Monoclonal AK2 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 WB, FACS, ELISA, IP, ICC 宿主: 小鼠 Monoclonal AK2 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP1 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-282) antibodyGP1BA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Flow Cytometry. Immunohistochemistry on frozen sections. Functional Application: The antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 15 mM Sodium Azide as preservative, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - 有效期
- 12 months
-
- 抗原
- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
- 别名
- CD42b / GPIbA (GP1BA 产品)
- 背景
- CD42b (GPIba) composes together with GPIbb, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.Synonyms: GP-Ib alpha, GPIb-alpha, Glycoprotein Ibalpha, Platelet glycoprotein Ib alpha chain
- UniProt
- P07359
-
