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Integrin beta 2 抗体 (Biotin)

This 小鼠 单克隆 antibody specifically detects Integrin beta 2 in FACS 和 IHC (fro). It exhibits reactivity toward 大鼠.
产品编号 ABIN120418
发货至: 中国
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北京 101111
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Quick Overview for Integrin beta 2 抗体 (Biotin) (ABIN120418)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 2 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

WT-3
  • 特异性

    This Antibody is specific for the β subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same β subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1

    亚型

    IgG1
  • 应用备注

    Immunoprecipitation. Flow cytometry. Immunohistochemistry on cryostat sections. Functional studies: in vivo/in vitro.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.2, with 0.09 % NaN3 and 0.5 % BSA.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    CD18 / ITGB2

    背景

    LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of α and β subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7

    基因ID

    25021

    NCBI登录号

    NP_036843

    UniProt

    Q9JI30

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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