FASL 抗体
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北京 101111
Quick Overview for FASL 抗体 (ABIN120319)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD178 cell surface antigen. Clone 14C2 is not reported to have a blocking function. We recommend the use of SM2268LE for functional studies.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry: 1/25 - 1/50, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, Results maybe enhanced using membrane permeabilisation. ELISA. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- CD178 / Fas Ligand
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背景
- CD178 is a 40 kDa glycoprotein also known as Fas ligand (CD95L). CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
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基因ID
- 356
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NCBI登录号
- NP_000630
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UniProt
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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