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CD59 抗体 (PE)

CD59 适用: 人 FACS 宿主: 大鼠 Monoclonal YTH53-1 PE
产品编号 ABIN119474
发货至: 中国
  • 抗原 See all CD59 抗体
    CD59
    适用
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    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CD59 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Clustered at the fourth leucocyte typing workshop to designation CD59. YTH53.1 reacts with CD59 transfectants. It enhances antibody-mediated lysis by homologous complement and reacts with GPI-linked antigen of 18-20 kDa size which is broadly expressed on human leucocytes and erythrocytes. Putative ligand for CD2.
    纯化方法
    Ion exchange chromatography
    免疫原
    Human Peripheral Blood T cells. Spleen cells from immunised DA rat fused with the Y3/Ag1.2.3 meloma cell line.
    克隆位点
    YTH53-1
    亚型
    IgG2b
    Top Product
    Discover our top product CD59 Primary Antibody
  • 应用备注
    Flow cytometry: We do not recommend using this antibody in lysed whole blood techniques due to inhibition of staining caused by CD59 expression on erythrocytes.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL distilled water
    缓冲液
    PBS, pH 7.2 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C.
  • 抗原
    CD59
    别名
    CD59 (CD59 产品)
    别名
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    背景
    CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
    基因ID
    966
    NCBI登录号
    NP_000602
    UniProt
    P13987
    途径
    Complement System
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