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CTLA4 抗体

This anti-CTLA4 antibody is a 小鼠 单克隆 antibody detecting CTLA4 in FACS, Func, IHC (fro) 和 EIA. Suitable for 人.
产品编号 ABIN118890
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CTLA4 抗体 (ABIN118890)

抗原

See all CTLA4 抗体
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CTLA4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

BNI3
  • 特异性

    Highly specific for CD152 (CTAL-4).

    免疫原

    Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig)

    亚型

    IgG2a
  • 应用备注

    Research studies by Microscopy or Flow cytometry, after in vitro activation of T cells with selected stimuli (Concanavalin A, or solid-phase fixed-CD3 + CD28 Mabs stimulation). Research studies on CTLA-4 expression on B cells and on CTLA-4 expression by Immunohistochemistry only on frozen tissue sections. Fluorescence microscopy or Flow cytometry: 2 μg/5x10e5 cells/test. Cytospin or immunohistochemistry on frozen tissue sections: Working concentration is 5-50 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL of distilled water.

    缓冲液

    PBS, pH 7.2, containing 1 mg/mL BSA as stabilizer without preservatives

    储存液

    Without preservative

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

    别名

    CD152 / CTLA4

    背景

    The cytolytic T-lymphocyte-associated antigen 4 (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA product, during a search for genes that were thought to be specifically expressed in cytotoxic T lymphocytes (1). CTLA-4 has a molecular weight close to 45 kDa (2). It is mainly expressed as a monomer (4), but may also be expressed as a disulfide-linked homodimer (2,3). CTLA-4 belongs to the CD28 receptor family (4,5).Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

    基因ID

    1493

    NCBI登录号

    NP_001032720

    UniProt

    P16410

    途径

    Cancer Immune Checkpoints
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