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CTLA4 抗体

CTLA4 适用: 人 FACS, Func, IHC (fro), EIA 宿主: 小鼠 Monoclonal BNI3 unconjugated
产品编号 ABIN118890
发货至: 中国
  • 抗原 See all CTLA4 抗体
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CTLA4 antibody is un-conjugated
    应用范围
    • 86
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    Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    Highly specific for CD152 (CTAL-4).
    免疫原
    Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig)
    克隆位点
    BNI3
    亚型
    IgG2a
    Top Product
    Discover our top product CTLA4 Primary Antibody
  • 应用备注
    Research studies by Microscopy or Flow cytometry, after in vitro activation of T cells with selected stimuli (Concanavalin A, or solid-phase fixed-CD3 + CD28 Mabs stimulation). Research studies on CTLA-4 expression on B cells and on CTLA-4 expression by Immunohistochemistry only on frozen tissue sections. Fluorescence microscopy or Flow cytometry: 2 μg/5x10e5 cells/test. Cytospin or immunohistochemistry on frozen tissue sections: Working concentration is 5-50 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL of distilled water.
    缓冲液
    PBS, pH 7.2, containing 1 mg/mL BSA as stabilizer without preservatives
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    别名
    CD152 / CTLA4 (CTLA4 产品)
    背景
    The cytolytic T-lymphocyte-associated antigen 4 (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA product, during a search for genes that were thought to be specifically expressed in cytotoxic T lymphocytes (1). CTLA-4 has a molecular weight close to 45 kDa (2). It is mainly expressed as a monomer (4), but may also be expressed as a disulfide-linked homodimer (2,3). CTLA-4 belongs to the CD28 receptor family (4,5).Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    基因ID
    1493
    NCBI登录号
    NP_001032720
    UniProt
    P16410
    途径
    Cancer Immune Checkpoints
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