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L-Selectin 抗体 (FITC)

This anti-L-Selectin antibody is a 小鼠 单克隆 antibody detecting L-Selectin in FACS. Suitable for 化学剂.
产品编号 ABIN118761
发货至: 中国

Quick Overview for L-Selectin 抗体 (FITC) (ABIN118761)

抗原

See all L-Selectin (SELL) 抗体
L-Selectin (SELL) (Selectin L (SELL))

适用

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化学剂

宿主

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小鼠

克隆类型

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单克隆

标记

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This L-Selectin antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

FMC46
  • 特异性

    This antibody recognizes CD62L, also known a L-selectin.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    PHA stimulated lymphoblasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    L-Selectin (SELL) (Selectin L (SELL))

    别名

    CD62L / L-Selectin

    物质类

    Chemical

    背景

    CD62L is a 74-95? kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.Synonyms: CD62 antigen-like family member L, LAM-1, LECAM1, LNHR, LYAM1, Leu-8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, SELL, TQ1, gp90-MEL

    基因ID

    6402

    NCBI登录号

    NP_000646

    UniProt

    P14151
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