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ITGA5 抗体

This anti-ITGA5 antibody is a 小鼠 单克隆 antibody detecting ITGA5 in FACS, IP 和 IHC (fro). Suitable for 人 和 犬.
产品编号 ABIN118715
发货至: 中国
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Quick Overview for ITGA5 抗体 (ABIN118715)

抗原

See all ITGA5 抗体
ITGA5 (Integrin, alpha 5 (ITGA5))

适用

  • 121
  • 80
  • 34
  • 2
  • 2
  • 1
  • 1
人, 犬

宿主

  • 100
  • 18
  • 10
  • 7
  • 4
小鼠

克隆类型

  • 78
  • 62
单克隆

标记

  • 68
  • 12
  • 11
  • 9
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITGA5 antibody is un-conjugated

应用范围

  • 87
  • 51
  • 45
  • 44
  • 24
  • 20
  • 17
  • 14
  • 14
  • 13
  • 10
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

JBS5
  • 特异性

    This antibody reacts with the Alpha 5 integrin. Has been shown to stimulate homotypic cellular aggregation of alpha 5 beta 1 positive lymphoid cell lines. It also inhibits the adherence of cells to fibronectin.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line.

    亚型

    IgG1
  • 应用备注

    Immunoprecipitation: 1-5 μg/mL. Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 1x10^6 cells in 100 μL of whole blood. Immunohistochemistry on Frozen Sections: 0.5-1 μg/mL. Recommended Positive Control: Human Endothelium. Functional assays: Removal of Sodium Azide is recommended prior to use.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ITGA5 (Integrin, alpha 5 (ITGA5))

    别名

    CD49e / ITGA5

    背景

    CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5), in platelets as glycoprotein IcIIa, and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling.Synonyms: CD49 antigen-like family member E, FNRA, Fibronectin receptor subunit alpha, Integrin alpha-5, Integrin alpha-F, VLA-5, VLA5

    基因ID

    3678

    NCBI登录号

    NP_002196

    UniProt

    P08648

    途径

    Integrin Complex
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