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CD44 抗体

CD44 适用: 人 FACS, WB, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal VFF-9 unconjugated
产品编号 ABIN118695
发货至: 中国
  • 抗原 See all CD44 抗体
    CD44
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    小鼠
    克隆类型
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    单克隆
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    This CD44 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Purified
    免疫原
    Human CD44v7.
    克隆位点
    VFF-9
    亚型
    IgG1
    Top Product
    Discover our top product CD44 Primary Antibody
  • 应用备注
    Flow cytometry: 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Western Blot. Immunohistochemistry on frozen sections: 1/50. Immunohistochemistry on paraffin sections: 1/50, This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skin.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD44
    别名
    CD44 (CD44 产品)
    别名
    CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody
    背景
    CD44 is a receptor for hyaluronic acid (HA). It mediates cell to cell and cell matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post translational modification events.Synonyms: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein I
    基因ID
    960
    NCBI登录号
    NP_000601
    UniProt
    P16070
    途径
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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