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CD27 抗体

CD27 适用: 人 FACS 宿主: 小鼠 Monoclonal LT27 unconjugated
产品编号 ABIN118578
发货至: 中国
  • 抗原 See all CD27 抗体
    CD27 (CD27 Molecule (CD27))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD27 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The antibody reacts with CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Precipitation methods and ion exchange chromatography
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human peripheral blood lymphocytes
    克隆位点
    LT27
    亚型
    IgG2a
    Top Product
    Discover our top product CD27 Primary Antibody
  • 应用备注
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD27 (CD27 Molecule (CD27))
    别名
    CD27 (CD27 产品)
    别名
    TNFRSF7 antibody, S152 antibody, Tnfrsf7 antibody, Tp55 antibody, S152. LPFS2 antibody, T14 antibody, CD27 molecule antibody, CD27 antigen antibody, CD27 antibody, Cd27 antibody
    背景
    CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
    基因ID
    939
    NCBI登录号
    NP_001233
    UniProt
    P26842
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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