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Integrin beta 2 抗体 (PE)

ITGB2 适用: 人, 犬 FACS 宿主: 大鼠 Monoclonal YFC118-3 PE
产品编号 ABIN118555
发货至: 中国
  • 抗原 See all Integrin beta 2 (ITGB2) 抗体
    Integrin beta 2 (ITGB2)
    适用
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    人, 犬
    宿主
    • 99
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    • 35
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    大鼠
    克隆类型
    • 132
    • 89
    • 2
    单克隆
    标记
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    This Integrin beta 2 antibody is conjugated to PE
    应用范围
    • 130
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    Flow Cytometry (FACS)
    特异性
    YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen as recognising the CD18 antigen. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Human neutrophils. Spleen cells from immunised LOU rats were fused with cells of the Y3/Ag.1.2.3 rat myeloma cell line.
    克隆位点
    YFC118-3
    亚型
    IgG2b
    Top Product
    Discover our top product ITGB2 Primary Antibody
  • 应用备注
    Flow cytometry: Use 10 μL of neat antibody to label 100 μL whole blood or 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    SM1076R: Restore with 1 mL distilled water. SM1076RT: Restore with 25 μL distilled water.
    缓冲液
    PBS, pH 7.2 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store antibody and control at -20 °C.
  • 抗原
    Integrin beta 2 (ITGB2)
    别名
    CD18 / ITGB2 (ITGB2 产品)
    背景
    The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
    基因ID
    3689
    NCBI登录号
    NP_000202
    UniProt
    P05107
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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