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CD31 抗体

This anti-CD31 antibody is a 仓鼠 单克隆 antibody detecting CD31 in FACS 和 Func. Suitable for 小鼠.
产品编号 ABIN118117
发货至: 中国

Quick Overview for CD31 抗体 (ABIN118117)

抗原

See all CD31 (PECAM1) 抗体
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

适用

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仓鼠

克隆类型

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单克隆

标记

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This CD31 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

2H8
  • 特异性

    This antibody reacts with the 130-140 kDa protein, PECAM-1 found on mouse monocytes, platelets, granulocytes and endothelial cells. Clone 2H8 effectively inhibits transmigration of activated polymorphonuclear cells and monocytes across the endothelium. In a mouse model for acute peritonitis clone 2H8 blocks acute inflammation.

    纯化方法

    Caprylic Acid Precipitation.

    亚型

    IgG
  • 应用备注

    Flow Cytometry (0.1 μg/mL): Use 5 μL of the suggested working dilution to label 100 μL ofwhole blood. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS without preservatives or stabilizers.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    别名

    CD31 / PECAM1

    背景

    CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). PECAM-1 is a 130-140 kD protein, found on mouse monocytes, platelets, granulocytes and endothelial cells.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule

    基因ID

    10090

    UniProt

    Q08481

    途径

    Regulation of Actin Filament Polymerization
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