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CD31 抗体

PECAM1 适用: 小鼠 FACS, Func 宿主: 仓鼠 Monoclonal 2H8 unconjugated
产品编号 ABIN118117
发货至: 中国
  • 抗原 See all CD31 (PECAM1) 抗体
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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    小鼠
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    仓鼠
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    单克隆
    标记
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    This CD31 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    This antibody reacts with the 130-140 kDa protein, PECAM-1 found on mouse monocytes, platelets, granulocytes and endothelial cells. Clone 2H8 effectively inhibits transmigration of activated polymorphonuclear cells and monocytes across the endothelium. In a mouse model for acute peritonitis clone 2H8 blocks acute inflammation.
    纯化方法
    Caprylic Acid Precipitation.
    克隆位点
    2H8
    亚型
    IgG
    Top Product
    Discover our top product PECAM1 Primary Antibody
  • 应用备注
    Flow Cytometry (0.1 μg/mL): Use 5 μL of the suggested working dilution to label 100 μL ofwhole blood. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS without preservatives or stabilizers.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    别名
    CD31 / PECAM1 (PECAM1 产品)
    背景
    CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). PECAM-1 is a 130-140 kD protein, found on mouse monocytes, platelets, granulocytes and endothelial cells.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
    基因ID
    10090
    UniProt
    Q08481
    途径
    Regulation of Actin Filament Polymerization
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