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L-Selectin 抗体

SELL 适用: 化学剂 FACS 宿主: 小鼠 Monoclonal DREG unconjugated
产品编号 ABIN1177376
发货至: 中国
  • 抗原 See all L-Selectin (SELL) 抗体
    L-Selectin (SELL) (Selectin L (SELL))
    适用
    • 90
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    化学剂
    宿主
    • 72
    • 55
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    • 1
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    小鼠
    克隆类型
    • 128
    • 45
    • 3
    单克隆
    标记
    • 71
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    This L-Selectin antibody is un-conjugated
    应用范围
    • 131
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    克隆位点
    DREG
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SELL Primary Antibody
  • 应用备注
    This NA/LE format is useful for in vitro functional studies.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Kishimoto, Warnock, Jutila, Butcher, Lane, Anderson, Smith: "Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro." in: Blood, Vol. 78, Issue 3, pp. 805-11, (1991) (PubMed).

  • 抗原
    L-Selectin (SELL) (Selectin L (SELL))
    别名
    CD62L (L-selectin) (SELL 产品)
    物质类
    Chemical
    背景
    Reacts with a 76-95 kDa glycoprotein referred to as L-selectin or LECAM-1. CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. Dreg-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen sections of peripheral, but not mucosal lymphoid tissue. It thus defines L-selectin as a human lymphocyte homing receptor for peripheral lymph node HEV. This antibody is routinely tested by flow cytometric analysis.
    Synonyms: L-selectin
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