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L-Selectin 抗体

This anti-L-Selectin antibody is a 小鼠 单克隆 antibody detecting L-Selectin in FACS. Suitable for 化学剂. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1177376
发货至: 中国

Quick Overview for L-Selectin 抗体 (ABIN1177376)

抗原

See all L-Selectin (SELL) 抗体
L-Selectin (SELL) (Selectin L (SELL))

适用

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化学剂

宿主

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小鼠

克隆类型

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单克隆

标记

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This L-Selectin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

DREG
  • 品牌

    BD Pharmingen™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    亚型

    IgG1 kappa
  • 应用备注

    This NA/LE format is useful for in vitro functional studies.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Kishimoto, Warnock, Jutila, Butcher, Lane, Anderson, Smith: "Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro." in: Blood, Vol. 78, Issue 3, pp. 805-11, (1991) (PubMed).

  • 抗原

    L-Selectin (SELL) (Selectin L (SELL))

    别名

    CD62L (L-selectin)

    物质类

    Chemical

    背景

    Reacts with a 76-95 kDa glycoprotein referred to as L-selectin or LECAM-1. CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. Dreg-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen sections of peripheral, but not mucosal lymphoid tissue. It thus defines L-selectin as a human lymphocyte homing receptor for peripheral lymph node HEV. This antibody is routinely tested by flow cytometric analysis.
    Synonyms: L-selectin
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