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CD42b 抗体

GP1BA 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal HIP1 unconjugated
产品编号 ABIN1177329
发货至: 中国
  • 抗原 See all CD42b (GP1BA) 抗体
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    适用
    • 70
    • 14
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    • 1
    • 1
    • 1
    • 1
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    • 1
    宿主
    • 36
    • 34
    • 2
    小鼠
    克隆类型
    • 39
    • 33
    单克隆
    标记
    • 42
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CD42b antibody is un-conjugated
    应用范围
    • 36
    • 33
    • 23
    • 13
    • 11
    • 7
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    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
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    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    克隆位点
    HIP1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GP1BA Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • 抗原
    CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
    别名
    CD42B (GP1BA 产品)
    背景
    The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor (vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding of vWF to platelets and partially inhibits collagen-induced aggregation.
    Synonyms: GP1BA, GPIbalpha, GP-Ib alpha, GPIb-alpha, CD42b-alpha, Glycocalicin, BSS
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