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ICAM2 抗体

ICAM2 适用: 小鼠 FACS, IP, IHC (fro), BR, IHC (f) 宿主: 大鼠 Monoclonal 3C4 unconjugated
产品编号 ABIN1177303
发货至: 中国
  • 抗原 See all ICAM2 抗体
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    适用
    • 65
    • 27
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    小鼠
    宿主
    • 52
    • 17
    • 14
    大鼠
    克隆类型
    • 52
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    单克隆
    标记
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    This ICAM2 antibody is un-conjugated
    应用范围
    • 50
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Transfected Cell Line
    克隆位点
    3C4
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ICAM2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos: "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness." in: Immunity, Vol. 10, Issue 1, pp. 9-19, (1999) (PubMed).

    Xu, Bickford, Luther, Carpenito, Takei, Springer: "Characterization of murine intercellular adhesion molecule-2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 12, pp. 4909-14, (1996) (PubMed).

  • 抗原
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    别名
    CD102 (ICAM2 产品)
    背景
    The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1.
    Synonyms: ICAM-2
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