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ITGA5 抗体

ITGA5 适用: 小鼠 FACS, IHC (fro), IF, BR, IHC (f) 宿主: 大鼠 Monoclonal 5H10-27 unconjugated
产品编号 ABIN1176992
发货至: 中国
  • 抗原 See all ITGA5 抗体
    ITGA5 (Integrin, alpha 5 (ITGA5))
    适用
    • 102
    • 61
    • 18
    • 2
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 85
    • 18
    • 8
    • 1
    • 1
    大鼠
    克隆类型
    • 76
    • 38
    单克隆
    标记
    • 56
    • 11
    • 11
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA5 antibody is un-conjugated
    应用范围
    • 82
    • 50
    • 39
    • 34
    • 15
    • 14
    • 13
    • 11
    • 10
    • 9
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Mouse mast cell line MC/9
    克隆位点
    5H10-27
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ITGA5 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Cukierman, Pankov, Stevens, Yamada: "Taking cell-matrix adhesions to the third dimension." in: Science (New York, N.Y.), Vol. 294, Issue 5547, pp. 1708-12, (2001) (PubMed).

    Yang, Hynes: "Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins." in: Molecular biology of the cell, Vol. 7, Issue 11, pp. 1737-48, (1997) (PubMed).

    Ruppert, Aigner, Hubbe, Yagita, Altevogt: "The L1 adhesion molecule is a cellular ligand for VLA-5." in: The Journal of cell biology, Vol. 131, Issue 6 Pt 2, pp. 1881-91, (1996) (PubMed).

    Rich, Van Nood, Lee: "Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2916-23, (1996) (PubMed).

    Gomez, Cano: "Expression of beta 1 integrin receptors in transformed mouse epidermal keratinocytes: upregulation of alpha 5 beta 1 in spindle carcinoma cells." in: Molecular carcinogenesis, Vol. 12, Issue 3, pp. 153-65, (1995) (PubMed).

    Hardy, Minguell: "Modulation of the adhesion of hemopoietic progenitor cells to the RGD site of fibronectin by interleukin 3." in: Journal of cellular physiology, Vol. 164, Issue 2, pp. 315-23, (1995) (PubMed).

    Halvorson, Coligan: "Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 10, pp. 4567-74, (1995) (PubMed).

    Kinashi, Springer: "Adhesion molecules in hematopoietic cells." in: Blood cells, Vol. 20, Issue 1, pp. 25-44, (1995) (PubMed).

  • 抗原
    ITGA5 (Integrin, alpha 5 (ITGA5))
    别名
    CD49e (ITGA5 产品)
    别名
    ITGA5 antibody, Cd49e antibody, Fnra antibody, VLA5 antibody, CD49e antibody, FNRA antibody, VLA5A antibody, Itga5_retired antibody, integrin subunit alpha 5 antibody, integrin alpha 5 (fibronectin receptor alpha) antibody, ITGA5 antibody, Itga5 antibody
    背景
    The 5H10-27 (MFR5) antibody reacts with the alpha5 chain of the integrin alpha5beta1 fibronectin receptor (CD49e/CD29, VLA-5) on thymocytes, activated T lymphocytes, mast cells, and a variety of mouse cell lines, but not splenocytes. Soluble 5H10-27 (MFR5) antibody has been reported to inhibit VLA-5-mediated functions in vitro. In addition, immobilized mAb 5H10-27 (MFR5) has been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3e antibody.
    Synonyms: Integrin alpha5 chain
    途径
    Integrin Complex
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