CXCR3 抗体
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北京 101111
Quick Overview for CXCR3 抗体 (ABIN1176889)
抗原
See all CXCR3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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免疫原
- Human CXCR3 Peptide
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亚型
- IgG1 kappa
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anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody
CXCR3 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5C10E6 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 301-367) antibodyCXCR3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibodyVerified CXCR3 适用: 人 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) antibodyCXCR3 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 4-50) antibodyCXCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-100) antibodyCXCR3 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibodyCXCR3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibodyCXCR3 适用: 人 FACS, WB 宿主: 兔 Monoclonal 24GB3480 unconjugated Recombinant Antibody
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibodyCXCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 140-167) antibodyCXCR3 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB23384 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig." in: European journal of immunology, Vol. 28, Issue 3, pp. 961-72, (1998) (PubMed).
: "The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions." in: The Journal of clinical investigation, Vol. 101, Issue 4, pp. 746-54, (1998) (PubMed).
: "Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes." in: The Journal of experimental medicine, Vol. 184, Issue 3, pp. 963-9, (1997) (PubMed).
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: "The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig." in: European journal of immunology, Vol. 28, Issue 3, pp. 961-72, (1998) (PubMed).
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- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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别名
- CD183
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背景
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The 1C6/CXCR3 monoclonal antibody specifically binds to human CD183, also known as the CXCR3 chemokine receptor. CD183 is a 40-41 kDa seven-transmembrane protein and member of the G protein-coupled receptor family. CD183 is expressed primarily on activated T cells that infiltrate inflammatory sites. It has also been detected on some circulating T cells, B cells, and NK cells. Reports show that some CXCR3-positive T cells also express CCR5 and are mostly CD45RO-positive cells. Three ligands for CXCR3 have been identified. They are CXCL9 (Mig/monokine induced by interferon-gamma), CXCL10 (IP-10/interferon-gamma inducible 10-kD protein), and CXCL11 (I-TAC/interferon-inducible T-cell alpha chemoattractant). These chemokines are produced by a variety of cells upon stimulation by IFN-gamma and interact with CXCR3 to mediate T-cell chemotaxis. This reagent has been reported to be suitable for immunohistochemical staining of acetone-fixed, frozen sections and/or formalin-fixed, paraffin-embedded tissue sections with citrate pretreatment. Clone 1C6/CXCR3 also cross reacts with a subset of peripheral blood lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. The distribution of lymphocytes is similar to that observed with CD183-positive peripheral blood lymphocytes from normal human donors. CXCR3 has been clustered as CD183 in the VIIth HLDA workshop.
Synonyms: CXCR3, C-X-C chemokine receptor type 3, GPR9, IP10R, MigR, CKRL2, CMKAR3
抗原
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