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CREB1 抗体 (N-Term)

Name: CREB1 抗体 (N-Term)
SKU: ABIN116948
Availability: OutOfStock

This anti-CREB1 antibody is a 兔多克隆 antibody detecting CREB1 in WB, IP, EIA 和 EMSA. Suitable for 人, 小鼠和大鼠.

Anti-CREB is shown to detect CREB-1 present in Raji B cell nuclear extract lysates. (CREB1 抗体 (N-Term))

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产品编号 ABIN116948

发货至: 中国

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中国
北京 101111

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Quick Overview for CREB1 抗体 (N-Term) (ABIN116948)

抗原

See all CREB1 抗体

CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CREB1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Electrophoretic Mobility-Shift Assay (EMSA)

Discover our top product CREB1 Primary Antibody

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N-Term

特异性

This product was prepared from monospecific antiserum by delipidation and Immunoadsorption against an E.coli lysate immobilized on agarose beads. This antibody may react non-specifically with other proteins. A partial cross-reactivity is observed against CREM-1 protein.

免疫原

CREB-1 (p43) peptide corresponding to a region near the N-terminus of the Human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
anti-cAMP Responsive Element Binding Protein 1 (CREB1) antibody
CREB1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G3 unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
CREB1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer142) antibody
CREB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
CREB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (AA 1-341) antibody
CREB1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (AA 1-95) antibody
CREB1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 5F2 unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (AA 1-341) antibody
CREB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F1-1B2 unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
CREB1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB05198 unconjugated

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
CREB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 3C11 unconjugated Recombinant Antibody

anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
CREB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: This antibody was assayed against a lysate of 1 x 10^6 Raji B cells byImmunoblot and found to be reactive against CREB-1 (p43), showing a 46 kDa band at adilution of 1/500-1/1,000 followed by reaction with Peroxidase conjugated anti-Rabbit IgG(H&L) [Goat] (Cat#R1364HRP)ELISA: 1/5,000-1/25,000. Immunoprecipitation. Gelshift: This antibody was tested in Gel Supershift Assay and found to be reactive againstCREB-1 (p43) using 0.5-1.0 μL per assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

2.56 mg/mL (by UV absorbance at 280 nm)

缓冲液

0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.
抗原

CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

别名

CREB1

背景

Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44 / 42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK 1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory. CREB knock out mice show diminished learning ability.Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1

基因ID

1385

NCBI登录号

NP_004370

UniProt

P16220

途径

TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation