PIDD 抗体
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北京 101111
Quick Overview for PIDD 抗体 (ABIN1169269)
抗原
See all PIDD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-PIDD (mouse), mAb (Lise-1)
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特异性
- Recognizes mouse PIDD.
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产品特性
- Monoclonal Antibody. Recognizes mouse PIDD. Isotype: Mouse IgG2bkappa. Clone: Lise-1. Applications: WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
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纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Mouse PIDD (Death Domain).
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亚型
- IgG2b kappa
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anti-P53-Induced Death Domain Protein (PIDD) (AA 1-85) antibody
PIDD 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) antibodyPIDD 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 694-885) antibodyPIDD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 666-915) antibodyPIDD 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 776-910) antibodyPIDD 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C5G8 unconjugated
anti-P53-Induced Death Domain Protein (PIDD) antibodyPIDD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 143-192) antibodyPIDD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 467-516) antibodyPIDD 适用: 人, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (Middle Region) antibodyPIDD 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- PIDD (P53-Induced Death Domain Protein (PIDD))
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别名
- PIDD
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背景
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Alternate Names/Synonyms: p53-induced Protein with a Death Domain, Leucine-rich Repeat and Death Domain-containing Protein, Lrdd
Product Description: PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
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UniProt
- Q9ERV7
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途径
- p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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