PIDD 抗体 (AA 776-910)
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北京 101111
Quick Overview for PIDD 抗体 (AA 776-910) (ABIN1169268)
抗原
See all PIDD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 776-910
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特异性
- Recognizes human and the native form of mouse PIDD. Detects bands of ~90 kDa (full length protein) and ~50 kDa (cleaved protein) by Western blot.
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交叉反应
- 人, 小鼠
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免疫原
- Recombinant human PIDD (Death Domain: aa 776-910).
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anti-P53-Induced Death Domain Protein (PIDD) (AA 1-85) antibody
PIDD 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) antibodyPIDD 适用: 人, 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 694-885) antibodyPIDD 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 666-915) antibodyPIDD 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 776-910) antibodyPIDD 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C5G8 unconjugated
anti-P53-Induced Death Domain Protein (PIDD) antibodyPIDD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 143-192) antibodyPIDD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 467-516) antibodyPIDD 适用: 人, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (AA 668-917) antibodyPIDD 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P53-Induced Death Domain Protein (PIDD) (Middle Region) antibodyPIDD 适用: 人, 大鼠, 小鼠, 豚鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, (2006) (PubMed).
: "PIDD mediates NF-kappaB activation in response to DNA damage." in: Cell, Vol. 123, Issue 6, pp. 1079-92, (2005) (PubMed).
: "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 843-6, (2004) (PubMed).
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: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, (2006) (PubMed).
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- PIDD (P53-Induced Death Domain Protein (PIDD))
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别名
- PIDD
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背景
- PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
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UniProt
- Q9HB75
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途径
- p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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