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PIDD 抗体 (AA 776-910)

Name: PIDD 抗体 (AA 776-910)
Brand: antibodies-online
SKU: ABIN1169268
Availability: OutOfStock

This anti-PIDD antibody is a 兔多克隆 antibody detecting PIDD in IHC, WB 和 IP. Suitable for 人和小鼠. This Primary Antibody has been cited in 3+ publications.

(3 references)

产品编号 ABIN1169268

发货至: 中国

Datasheet as PDF

Quick Overview for PIDD 抗体 (AA 776-910) (ABIN1169268)

抗原

See all PIDD 抗体

PIDD (P53-Induced Death Domain Protein (PIDD))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This PIDD antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)

Discover our top product PIDD Primary Antibody

抗原表位
15

3

2

2

1

1

1

1

1

1

1
AA 776-910

特异性

Recognizes human and the native form of mouse PIDD. Detects bands of ~90 kDa (full length protein) and ~50 kDa (cleaved protein) by Western blot.

交叉反应

人, 小鼠

免疫原

Recombinant human PIDD (Death Domain: aa 776-910).
anti-P53-Induced Death Domain Protein (PIDD) (AA 1-85) antibody
PIDD 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) antibody
PIDD 适用: 人, 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (AA 694-885) antibody
PIDD 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (AA 666-915) antibody
PIDD 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (AA 776-910) antibody
PIDD 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C5G8 unconjugated

anti-P53-Induced Death Domain Protein (PIDD) antibody
PIDD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (AA 143-192) antibody
PIDD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (AA 467-516) antibody
PIDD 适用: 人, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (AA 668-917) antibody
PIDD 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-P53-Induced Death Domain Protein (PIDD) (Middle Region) antibody
PIDD 适用: 人, 大鼠, 小鼠, 豚鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

In PBS containing 10 % glycerol and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

有效期

12 months
Milleron, Bratton: "Heat shock induces apoptosis independently of any known initiator caspase-activating complex." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 16991-7000, (2006) (PubMed).

Janssens, Tinel, Lippens, Tschopp: "PIDD mediates NF-kappaB activation in response to DNA damage." in: Cell, Vol. 123, Issue 6, pp. 1079-92, (2005) (PubMed).

Tinel, Tschopp: "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 843-6, (2004) (PubMed).
抗原

PIDD (P53-Induced Death Domain Protein (PIDD))

别名

PIDD

背景

PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.

UniProt

Q9HB75

途径

p53 Pathway, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity