DLL4 抗体 (Extracellular Domain)
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北京 101111
Quick Overview for DLL4 抗体 (Extracellular Domain) (ABIN1169263)
抗原
See all DLL4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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原理
- anti-DLL4 (human), mAb (DL86-3AG)
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特异性
- Recognizes human DLL4.
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产品特性
- Monoclonal Antibody. Recognizes human DLL4. Isotype: Mouse IgG1kappa. Clone: DL86-3AG. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human DLL4 (extracellular domain).
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- DLL4 (delta-Like 4 (DLL4))
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别名
- DLL4
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背景
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Alternate Names/Synonyms: Delta-like Protein 4, Delta4
Product Description: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
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UniProt
- Q9NR61
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途径
- Notch Signaling
抗原
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