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DLL4 抗体 (Extracellular Domain)

This 小鼠 单克隆 antibody specifically detects DLL4 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN1169263
发货至: 中国
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Quick Overview for DLL4 抗体 (Extracellular Domain) (ABIN1169263)

抗原

See all DLL4 抗体
DLL4 (delta-Like 4 (DLL4))

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This DLL4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

DL86-3AG
  • 抗原表位

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    Extracellular Domain

    原理

    anti-DLL4 (human), mAb (DL86-3AG)

    特异性

    Recognizes human DLL4.

    产品特性

    Monoclonal Antibody. Recognizes human DLL4. Isotype: Mouse IgG1kappa. Clone: DL86-3AG. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human DLL4 (extracellular domain).

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4.

    储存液

    Without preservative

    注意事项

    After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    -20°C

    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    DLL4 (delta-Like 4 (DLL4))

    别名

    DLL4

    背景

    Alternate Names/Synonyms: Delta-like Protein 4, Delta4

    Product Description: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

    UniProt

    Q9NR61

    途径

    Notch Signaling
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