DLL4 抗体
(1 reference)Our Local Distributor
北京 101111
Quick Overview for DLL4 抗体 (ABIN1169261)
抗原
See all DLL4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- anti-DLL4 (mouse), mAb (9A1.5)
-
特异性
- Recognizes mouse DLL4.
-
产品特性
- Monoclonal Antibody. Recognizes mouse DLL4. Isotype: Rat IgG1kappa. Clone: 9A1.5. Applications: FACS, ICC. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
-
纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
-
纯度
- >95 % (SDS-PAGE)
-
免疫原
- Recombinant mouse DLL4:Fc.
-
亚型
- IgG1 kappa
-
-
anti-delta-Like 4 (DLL4) (AA 313-439) antibody
DLL4 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4A11F8 unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4A11G2 unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4A11F8 unconjugated
anti-delta-Like 4 (DLL4) (AA 215-331) antibodyDLL4 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 4 (DLL4) (AA 625-652), (C-Term) antibodyDLL4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23696 unconjugated
anti-delta-Like 4 (DLL4) (Internal Region) antibodyDLL4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal 4A11F8-4A11G2 unconjugated
anti-delta-Like 4 (DLL4) (AA 123-221) antibodyDLL4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-delta-Like 4 (DLL4) (AA 123-221) antibodyDLL4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
-
有效期
- 12 months
-
-
-
: "Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 12, pp. 8199-203, (2008) (PubMed).
-
-
- DLL4 (delta-Like 4 (DLL4))
-
别名
- DLL4
-
背景
-
Alternate Names/Synonyms: Delta-like Protein 4, Delta4
Product Description: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
-
UniProt
- Q9JI71
-
途径
- Notch Signaling
抗原
-
