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DLL4 抗体

This anti-DLL4 antibody is a 大鼠 单克隆 antibody detecting DLL4 in FACS 和 ICC. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1169261
发货至: 中国

Quick Overview for DLL4 抗体 (ABIN1169261)

抗原

See all DLL4 抗体
DLL4 (delta-Like 4 (DLL4))

适用

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小鼠

宿主

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  • 1
大鼠

克隆类型

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  • 1
单克隆

标记

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This DLL4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

9A1-5
  • 特异性

    Recognizes mouse DLL4.

    交叉反应

    小鼠

    纯化方法

    Purified from concentrated hybridoma tissue culture supernatant.

    纯度

    >95 % (SDS-PAGE)

    免疫原

    Recombinant mouse DLL4:Fc.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    In PBS containing 10 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • Fiorini, Ferrero, Merck, Favre, Pierres, Luther, MacDonald: "Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 12, pp. 8199-203, (2008) (PubMed).

  • 抗原

    DLL4 (delta-Like 4 (DLL4))

    别名

    DLL4

    背景

    The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

    UniProt

    Q9JI71

    途径

    Notch Signaling
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