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LAG3 抗体 (N-Term) (Atto 647N)

This Atto 647N-conjugated 小鼠 单克隆 anti-LAG3 antibody (Clone 17B4) specifically detects LAG3 in ICC 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1169111
发货至: 中国
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Quick Overview for LAG3 抗体 (N-Term) (Atto 647N) (ABIN1169111)

抗原

See all LAG3 抗体
LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LAG3 antibody is conjugated to Atto 647N

应用范围

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Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

17B4
  • 抗原表位

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    N-Term

    特异性

    Recognizes human LAG-3.

    交叉反应

    纯度

    >95 % (SDS-PAGE)

    免疫原

    Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 647N shows red fluorescence (lambdaabs (max): 645nm, lambdaem (max): 669nm, epsilonmax: 120'000).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    In PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: +4°C
    Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

    有效期

    12 months
  • 抗原

    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

    别名

    LAG-3

    背景

    Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

    UniProt

    P18627

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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