LAG3 抗体 (N-Term) (Atto 488)
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北京 101111
Quick Overview for LAG3 抗体 (N-Term) (Atto 488) (ABIN1169108)
抗原
See all LAG3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- anti-LAG-3 (human), mAb (17B4) (ATTO 488)
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特异性
- Recognizes human LAG-3.
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产品特性
- Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, ICC. Liquid. In PBS containing 0.02 % sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
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亚型
- IgG1 kappa
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anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 500-525) antibody
LAG3 适用: 人 WB, IHC, ICC, IP, FACS, IF (p), mIF 宿主: 兔 Monoclonal BLR027F unconjugated Recombinant Antibody
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21775 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) antibodyLAG3 适用: 人 WB, IHC, ICC, IP, FACS, IF (p) 宿主: 兔 Monoclonal BLR028F unconjugated Recombinant Antibody
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 66-199) antibodyLAG3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4H6A3 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8B12E10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 250-300) antibodyLAG3 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Monoclonal BLR261L unconjugated Recombinant Antibody
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibodyLAG3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibodyLAG3 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) antibodyLAG3 适用: 人 ELISA 宿主: 小鼠 Monoclonal LAG3-3261 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (lambdaabs (max): 501nm, lambdaem (max): 523nm, epsilonmax: 90'000).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.Protect from light.
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储存条件
- 4 °C
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储存方法
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+4°C
+4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
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有效期
- 12 months
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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别名
- LAG-3
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背景
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Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223
Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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UniProt
- P18627
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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