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LAG3 抗体 (N-Term) (FITC)

The FITC-conjugated 小鼠 单克隆 anti-LAG3 antibody (Clone 17B4) (ABIN1169106) specifically detects LAG3 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1169106
发货至: 中国
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Quick Overview for LAG3 抗体 (N-Term) (FITC) (ABIN1169106)

抗原

See all LAG3 抗体
LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LAG3 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

17B4
  • 抗原表位

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    N-Term

    原理

    anti-LAG-3 (human), mAb (17B4) (FITC)

    特异性

    Recognizes human LAG-3.

    产品特性

    Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS. Liquid. In PBS containing 0.02 % sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

    纯度

    >95 % (SDS-PAGE)

    免疫原

    Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    In PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.Protect from light.

    储存条件

    4 °C

    储存方法

    +4°C

    +4°C

    Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

    有效期

    12 months
  • 抗原

    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

    别名

    LAG-3

    背景

    Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223

    Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

    UniProt

    P18627

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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