LAG3 抗体 (N-Term)
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北京 101111
Quick Overview for LAG3 抗体 (N-Term) (ABIN1169104)
抗原
See all LAG3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- anti-LAG-3 (human), mAb (blocking) (17B4) (preservative free)
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特异性
- Recognizes human LAG-3.
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产品特性
- Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, FUNC (Blocking), ICC, IHC, IP, WB. Liquid. In PBS. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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纯度
- >95 % (SDS-PAGE)
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内毒素水平
- <0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).
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免疫原
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
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亚型
- IgG1 kappa
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anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 500-525) antibody
LAG3 适用: 人 WB, IHC, ICC, IP, FACS, IF (p), mIF 宿主: 兔 Monoclonal BLR027F unconjugated Recombinant Antibody
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21775 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 23-450) antibodyLAG3 适用: 人 WB, IHC, ICC, IP, FACS, IF (p) 宿主: 兔 Monoclonal BLR028F unconjugated Recombinant Antibody
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 66-199) antibodyLAG3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4H6A3 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 103-132) antibodyLAG3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 29-450) antibodyLAG3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8B12E10 unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 250-300) antibodyLAG3 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Monoclonal BLR261L unconjugated Recombinant Antibody
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 1-360) antibodyLAG3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) (AA 201-300) antibodyLAG3 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte-Activation Gene 3 (LAG3) antibodyLAG3 适用: 人 ELISA 宿主: 小鼠 Monoclonal LAG3-3261 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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别名
- LAG-3
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背景
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Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223
Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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UniProt
- P18627
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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