LAG3 抗体 (N-Term)
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北京 101111
Quick Overview for LAG3 抗体 (N-Term) (ABIN1169104)
抗原
See all LAG3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- Recognizes human LAG-3.
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交叉反应
- 人
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纯度
- >95 % (SDS-PAGE)
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内毒素水平
- <0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).
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免疫原
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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别名
- LAG-3
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背景
- Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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UniProt
- P18627
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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