NAMPT 抗体 (Biotin)
Quick Overview for NAMPT 抗体 (Biotin) (ABIN1169029)
抗原
See all NAMPT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes human, mouse and rat Nampt.
-
交叉反应
- 人, 小鼠, 大鼠
-
过滤
- 0.2 μm filtered
-
免疫原
- Recombinant human Nampt (visfatin/PBEF).
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
-
-
- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
-
别名
- Nampt (Visfatin/PBEF)
-
背景
- Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52 kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
-
UniProt
- P43490
抗原
-