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NAMPT 抗体

This anti-NAMPT antibody is a 兔 多克隆 antibody detecting NAMPT in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1169025
发货至: 中国

Quick Overview for NAMPT 抗体 (ABIN1169025)

抗原

See all NAMPT 抗体
NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

适用

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宿主

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克隆类型

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多克隆

标记

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This NAMPT antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 特异性

    Recognizes human Nampt. Detects a band of ~54 kDa by Western blot.

    交叉反应

    交叉反应 (详细)

    Weakly cross-reacts with mouse Nampt.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human Nampt (visfatin/PBEF).
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • Moschen, Kaser, Enrich, Mosheimer, Theurl, Niederegger, Tilg: "Visfatin, an adipocytokine with proinflammatory and immunomodulating properties." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 3, pp. 1748-58, (2007) (PubMed).

    Nowell, Richards, Fielding, Ognjanovic, Topley, Williams, Bryant-Greenwood, Jones: "Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis." in: Arthritis and rheumatism, Vol. 54, Issue 7, pp. 2084-95, (2006) (PubMed).

    Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: "Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1." in: FEBS letters, Vol. 580, Issue 17, pp. 4105-13, (2006) (PubMed).

  • 抗原

    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

    别名

    Nampt (Visfatin/PBEF)

    背景

    Nampt also known as pre-B cell colony-enhancing factor 1 (PBEF1) or visfatin is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

    UniProt

    P43490
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