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GDNF 抗体 (Biotin)

This anti-GDNF antibody is a 兔 多克隆 antibody detecting GDNF in WB, IHC (fro) 和 EIA. Suitable for 人.
产品编号 ABIN116019
发货至: 中国

Quick Overview for GDNF 抗体 (Biotin) (ABIN116019)

抗原

See all GDNF 抗体
GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

适用

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宿主

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克隆类型

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多克隆

标记

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This GDNF antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
  • 特异性

    Human Glial Derived Neurotrophic Factor.

    纯化方法

    Affinity chromatography.

    免疫原

    Highly pure (>98%) recombinant hGDNF.
  • 应用备注

    ELISA: To detect hGDNF by direct ELISA (using 100 ml/well antibody solution) this GDNFantibody can be used at a concentration of 0.15-0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthGDNF. Western Blot: To detect hGDNF by Western Blot analysis this GDNF antibody can be used ata concentration of 0.1-0.2 mg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hGDNF is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives.

    储存液

    Without preservative

    注意事项

    Centrifuge vial prior to opening! This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Store the antibody at 2-8 °C. DO NOT FREEZE!
  • 抗原

    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

    别名

    GDNF

    背景

    Glial cell line derived neurotrophic factor (GDNF) is a highly conserved neurotrophic factor that is a distant member of the TGF beta superfamily. The GDNF gene product is processed to a disulphide-linked homodimer, which is a ligand for the RET protooncogene. GDNF protects and repairs dopamine-containing neurons, which degenerate in Parkinson's disease, and motor neurons, which die in amyotrophic lateral sclerosis. The use of GDNF in the treatment of Parkinson's disease has shown promise in the clinic. Treatment of spinal cord injuries with GDNF has also produced neurological improvement.Synonyms: ATF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor

    基因ID

    2668

    NCBI登录号

    NP_000505

    UniProt

    P39905

    途径

    RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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