Pleiotrophin 抗体
(1 reference)Quick Overview for Pleiotrophin 抗体 (ABIN115512)
抗原
See all Pleiotrophin (PTN) 抗体适用
宿主
克隆类型
标记
应用范围
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序列
- MKHHHHHHHM LVPRGSGKKE KPEKKVKKSD CGEWQWSVCV PTSGDCGLGT REGTRTGAEC KQTMKTQRCK IPCNWKKQFG AECKYQFQAW GECDLNTALK TRTGSLKRAL HNAECQKTVT ISKPCGKLTK PKPQAESKKK KKEGKKQEKM LD
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特异性
- This antibody reacts to Pleiotrophin.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Recombinant human OSF-1 (E.coli)
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anti-Pleiotrophin (PTN) (AA 45-154) antibody
PTN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Pleiotrophin (PTN) (AA 33-168) antibodyPTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 101-168) antibodyPTN 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 33-168) antibodyPTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 33-168) antibodyPTN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 150-168), (C-Term) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (AA 127-154), (C-Term) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB14477 unconjugated
anti-Pleiotrophin (PTN) (C-Term) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) antibodyPTN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pleiotrophin (PTN) (Internal Region) antibodyVerified PTN 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 0.05 mL of deionized water.
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浓度
- 1.0 mg/mL
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缓冲液
- 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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: "Oral administration of high molecular weight hyaluronan (900 kDa) controls immune system via Toll-like receptor 4 in the intestinal epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24751-8, (2010) (PubMed).
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: "Oral administration of high molecular weight hyaluronan (900 kDa) controls immune system via Toll-like receptor 4 in the intestinal epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24751-8, (2010) (PubMed).
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- Pleiotrophin (PTN)
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别名
- Pleiotrophin / PTN
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背景
- Pleiotrophin (Osteoblast-Specific Factor-1, OSF-1) contains 136 amino acid residues. The sequence is very rich in cationic amino acids (24 % of the residues), lysine cluster sequences are found in the N-terminal and Cterminal ends of the structure. The OSF-1 gene was shown by Northern blotting analysis to be expressed in mouse calvarial osteoblastenriched cells and in mouse brain tissues, but not in thymus, spleen, kidney, liver, lung, testis or heart. Pliotrophin has the ability to promote adhesion, migration, expansion, and differentiation of human osteoprogenitor cells. In addition to certain types of cancer, the embryonic growth and differentiation factor pleiotrophin is found also in adults in inflammatory diseases. In osteoarthritis, pleiotrophin is especially expressed in early stages, and its concentrations in the synovial fluid could serve as a marker for the progress of the disease. Pleitrophin might be involved in cartilage repair in osteoarthritis, in particular, in earlier stages. Total 152 AA. MW: 17.3 kDa. N-Terminal His-tag and thrombin cleavage site 16 AA (highlighted).Synonyms: HB-GAM, HBBM, HBGF-8, HBNF-1, HBNF1, Heparin-binding brain mitogen, Heparin-binding growth factor 8, Heparin-binding growth-associated molecule, Heparin-binding neurite outgrowth-promoting factor 1, NEGF1, OSF-1, OSF1, Osteoblast-specific factor 1
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基因ID
- 5764
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NCBI登录号
- NP_002816
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UniProt
- P21246
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途径
- RTK signaling
抗原
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