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AMACR 抗体

This 兔 多克隆 antibody specifically detects AMACR in IHC (p) 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN115447
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for AMACR 抗体 (ABIN115447)

抗原

See all AMACR 抗体
AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

适用

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宿主

  • 88
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克隆类型

  • 92
  • 55
多克隆

标记

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This AMACR antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Reacts to P504S Alpha-Methylacyl-CoA Racemace.
    Cellular Localization: Cytoplasmic.

    纯化方法

    Purified

    免疫原

    A synthetic human AMACR peptide.
  • 应用备注

    Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: 1/25-1/50 in anABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Prostate carcinoma.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

    别名

    AMACR / RACE

    背景

    P504S (AMARC) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.Synonyms: 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, P504S

    基因ID

    23600

    NCBI登录号

    NP_055139

    UniProt

    Q9UHK6

    途径

    Monocarboxylic Acid Catabolic Process
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