AMACR 抗体
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北京 101111
Quick Overview for AMACR 抗体 (ABIN115447)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
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Reacts to P504S Alpha-Methylacyl-CoA Racemace.
Cellular Localization: Cytoplasmic. -
纯化方法
- Purified
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免疫原
- A synthetic human AMACR peptide.
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应用备注
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Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: 1/25-1/50 in anABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Prostate carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- AMACR / RACE
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背景
- P504S (AMARC) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.Synonyms: 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, P504S
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基因ID
- 23600
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NCBI登录号
- NP_055139
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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