FLT1 抗体 (Extracellular Domain)
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Quick Overview for FLT1 抗体 (Extracellular Domain) (ABIN115152)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- The monoclonal antibody will recognize recombinant and naturally occurring form of Human VEGFR-1/Flt-1.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Recombinant Human soluble extracellular Flt-1 protein (D5) (Cat.-No DA3539)
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亚型
- IgG1
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anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 1162-1260) antibody
FLT1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 20-300) antibodyFLT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 1100-1200) antibodyFLT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (pTyr1213) antibodyFLT1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) antibodyFLT1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB5440 unconjugated Recombinant Antibody
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) antibodyKD Validated FLT1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7115 unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 1-687) antibodyFLT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) antibodyFLT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16736 unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (pTyr1048) antibodyFLT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1) (AA 18-308) antibodyFLT1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA (1.5-8 μg/mL), Western blotting (1-10 μg/mL), Immunoprecipitation (1-5 μg/mL lysateor reaction volume).
Other applications not tested.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with distilled sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS pH 7.4 containing no preservative
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- VEGFR-1 / Flt-1
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背景
- Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells, but mediates signals for differentiation. Interestingly a naturally occuring soluble variant of VEGFR-1 (sVEGFR-1) was found in HUVE supernatants in 1996, which is generated by alternative splicing of the flt-1 mRNA.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
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基因ID
- 2321
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NCBI登录号
- NP_001153392
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UniProt
- P17948
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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