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alpha 2 Macroglobulin 抗体

This anti-alpha 2 Macroglobulin antibody is a 绵羊 多克隆 antibody detecting alpha 2 Macroglobulin in EIA 和 IHC (fro). Suitable for 人.
产品编号 ABIN113581
发货至: 中国

Quick Overview for alpha 2 Macroglobulin 抗体 (ABIN113581)

抗原

See all alpha 2 Macroglobulin (A2M) 抗体
alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

适用

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宿主

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绵羊

克隆类型

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多克隆

标记

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This alpha 2 Macroglobulin antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    This antibody detects alpha-2-Macroglobulin.

    纯化方法

    Ammonium Sulphate fractionation

    免疫原

    Native Alpha-2 Macroglobulin
  • 应用备注

    Immunohistochemistry on frozen sections (1: 20 - 1: 200). ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    28.3 mg/mL

    缓冲液

    PBS, pH 7.2, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

    别名

    alpha-2-Macroglobulin

    背景

    Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes.Synonyms: A2M, Alpha 2 macroglobulin, Alpha-2-M, CPAMD5, PZP-like alpha-2-macroglobulin domain-containing

    基因ID

    2

    NCBI登录号

    NP_000005

    UniProt

    P01023

    途径

    Lipid Metabolism
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