C3 抗体 (HRP)
Quick Overview for C3 抗体 (HRP) (ABIN113306)
抗原
See all C3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Complement 3c, a polypeptide fragment which is present in C3.
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纯化方法
- Affinity chromatography on Protein G.
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免疫原
- Complement 3c.
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anti-Complement Component 3 (C3) (AA 1000-1326) antibody
C3 适用: 人 WB, IHC, IP, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1551-1663) antibodyC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (fro), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1644) antibodyC3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) (C-Term) antibodyC3 适用: 人 WB, IP, ICC, IF, IHC (p), ISub 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 23-300) antibodyC3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 965-1303) antibodyC3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1645) antibodyC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) antibodyC3 适用: 小鼠 WB, IP, FACS, IF, IA 宿主: 大鼠 Monoclonal 11H9 unconjugated
anti-Complement Component 3 (C3) (AA 966-1313) antibodyC3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1353-1382) antibodyC3 适用: 人 WB 宿主: 小鼠 Monoclonal 567CT11-2-3 unconjugated
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应用备注
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Suitable for ELISA (1/200-1/800) and Western blotting (1/500-1/2000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2, containing 0.01 % Thiomersal as preservative.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized product at 2 - 8 °C. Following reconstitution store at -20 °C.
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- C3 (Complement Component 3 (C3))
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别名
- Complement C3
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背景
- C3 plays a central role in the activation of the complement system. Processing of C3 by C3 convertase is the central reaction in both classical and alternative complement pathways, resulting in C3a and C3b. C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates, and help to initiate the complement cascade, potentially resulting in cellular apoptosis. C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released. Then iC3b is slowly cleaved (possibly by factor I) to form C3c and C3dg. Defects in C3 can result in susceptibility to pyogenic infection.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
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基因ID
- 718
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NCBI登录号
- NP_000055
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UniProt
- P01024
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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