CGRP 抗体 (AA 23-37)
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北京 101111
Quick Overview for CGRP 抗体 (AA 23-37) (ABIN112616)
抗原
See all CGRP (CALCA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-37
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特异性
- Recognizes Calcitonin gene-related peptide, also known as CGRP, a neuropeptide that acts as a vasodilator and may play a role in migraine. This antibody is reactive with both whole molecule (1-37) and the C-terminal (23-37). Specifically visualises CGRP in brain cells.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Synthetic Rat Tyr-CGRP (23-37) conjugated to gamma globulin
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亚型
- IgG
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anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-130) antibody
CALCA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-141) antibodyCALCA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 52-141) antibodyCALCA 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 65-130) antibodyCALCA 适用: 人, 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-134) antibodyCALCA 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (Internal Region) antibodyCALCA 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 83-119), (C-Term) antibodyCALCA 适用: 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) antibodyCALCA 适用: 大鼠 ELISA, ICC 宿主: 小鼠 Monoclonal 4901 unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) antibodyCALCA 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4G1H7 unconjugated
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应用备注
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ELISA (1/500-1/2500). Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 5.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
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别名
- CGRP / CALCA
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背景
- CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat, it can modulate acetylcholine receptor function at the neuromuscular junction, it has been demonstrated to block tolerance to morphine, and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.Synonyms: Alpha-type CGRP, CALC1, CGRP-I, Calcitonin gene-related peptide I
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基因ID
- 24241
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NCBI登录号
- NP_001029127
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UniProt
- P01256
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途径
- Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour
抗原
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