CGRP 抗体
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- 抗原 See all CGRP (CALCA) 抗体
- CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CGRP antibody is un-conjugated
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应用范围
- Immunocytochemistry (ICC)
- 特异性
- Specific for Calcitonin Gene Related Peptide. Also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP). Suggested positive controls are dorsal root ganglia, pancreas and gut. Notes: This antibody is an excellent tool for immunohistochemistry and for multiple labeling immunofluorescence of peripheral tissue like stomach, intestine, pancreas, sensory ganglia, and all the regions of the body that are innervated by primary afferent neurons as well as central nervous tissue. It is expected that the antibody will react with most mammals.
- 交叉反应
- 人, 大鼠
- 预测反应
- most mammals
- 纯化方法
- Protein G purified culture supernatant
- 免疫原
- Purified rat alpha-CGRP
- 克隆位点
- 4901
- 亚型
- IgG2a
- Top Product
- Discover our top product CALCA Primary Antibody
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anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-141) antibody
CALCA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-130) antibodyCALCA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 52-141) antibodyCALCA 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-141) antibodyCALCA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 65-130) antibodyCALCA 适用: 人, 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-134) antibodyCALCA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) antibodyCALCA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (Internal Region) antibodyCALCA 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 80-141) antibodyCALCA 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 85-116) antibodyCALCA 适用: 犬 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended Dilution: ICC: 1:50-1:100 Quality Control: ICC performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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- 抗原
- CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
- 别名
- CALCA (CALCA 产品)
- 别名
- CALC1 antibody, CGRP antibody, CGRP-I antibody, CGRP1 antibody, CT antibody, KC antibody, CALC antibody, CALCA antibody, CALC3 antibody, ci-ct antibody, calca antibody, CA antibody, CGRP-1 antibody, Calc antibody, Calc1 antibody, Cgrp antibody, Ct antibody, Ctn antibody, calcitonin antibody, CAL6 antibody, Cal1 antibody, RATCAL6 antibody, CGRPI antibody, calc antibody, cgrp antibody, zgc:92886 antibody, calcitonin related polypeptide alpha antibody, calcitonin related polypeptide beta antibody, calcitonin-related polypeptide alpha antibody, calcitonin antibody, calcitonin/calcitonin-related polypeptide, alpha antibody, calcitonin-related polypeptide beta antibody, calcitonin gene-related peptide 2 antibody, CALCA antibody, CALCB antibody, ci-ct antibody, calca antibody, Calca antibody, LOC100008771 antibody
- 背景
- Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993)
- 基因ID
- 24241
- UniProt
- P01256
- 途径
- Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour
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