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JUP 抗体

JUP 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 斑马鱼 WB, IF, IHC (p), IP, IHC (fro) 宿主: 小鼠 Monoclonal PG 5-1 unconjugated
产品编号 ABIN112236
发货至: 中国
  • 抗原 See all JUP 抗体
    JUP (Junction Plakoglobin (JUP))
    适用
    • 150
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    人, 小鼠, 大鼠, 小鸡, Cow, 斑马鱼
    宿主
    • 94
    • 56
    • 2
    • 1
    小鼠
    克隆类型
    • 84
    • 69
    单克隆
    标记
    • 69
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    This JUP antibody is un-conjugated
    应用范围
    • 113
    • 54
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    • 32
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    • 22
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    • 11
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    PG 5.1 represents an excellent marker for all forms of intercellular adhering junctions, such as: Desmosomes of epithelial and myocardial cells (incl. cultured cells), Zonulae and fasciae adherentes of epithelia, endothelia of blood vessels and myocardial cells, adherens-type junctions (e.g. lens tissue, pigmented retinal cells, Sertoli cells of testis). The PG 5.1 epitope maps within the C-terminus at the extreme end of repeat 13 (aa 632-687) of plakoglobin. Polypeptide Reacting: Mr 83 000 Plakoglobin, "band 5" polypeptide of intercellular adhering junctions (identical to γ-catenin). Reactivity on Cultured Cell Lines: Cell cultures forming monolayers (from tested species cited below).
    交叉反应 (详细)
    Species reactivity (tested):Human, Bovine, Rat, Mouse, Chicken and Zebrafish.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Plakoglobin, "band 5" protein from Bovine snout epidermis
    克隆位点
    PG 5-1
    亚型
    IgG2b
    Top Product
    Discover our top product JUP Primary Antibody
  • 应用备注
    Immunoblotting. Immunoprecipitation. Immunofluorescence Microscopy: 1/5 (1 h at RT). Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in 1 mL distilled water
    缓冲液
    Final solution contains PBS buffer, pH 7.4 with 0.09 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    JUP (Junction Plakoglobin (JUP))
    别名
    Junction Plakoglobin (JUP 产品)
    别名
    ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody
    背景
    Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.Synonyms: CTNNG, Catenin gamma, DP3, Desmoplakin III, Desmoplakin-3, JUP
    基因ID
    3728
    NCBI登录号
    NP_002221
    UniProt
    P14923
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location
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