CEACAM5 抗体
Our Local Distributor
北京 101111
Quick Overview for CEACAM5 抗体 (ABIN111951)
抗原
See all CEACAM5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- C19 is useful to detect CEA in malignant adenocarcinoma, notably in the gastro-intestinal tract. Clinical relevance is also found in breast-, lung-, prostatic-,ovarian- and other carcinomas of endodermal origin (stomach, liver, pancreas). Contrary to some other antibodies, C19 stains granulocytes in blood smears and tonsils, as well as epithelial cells.
-
纯化方法
- Affinity chromatography.
-
亚型
- IgG1
-
-
-
-
应用备注
-
Suitable for Immunohistochemistry on paraffin embedded sections (0.1 μg/mL, 1/4000). Microwave pretreatment forantigen retrieval is recommended. Suggested positive control: Human colon carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
实验流程
- Protocol with formalin-fixed, paraffin-embedded sections: The whole procedure is performed at room temperature
-
限制
- 仅限研究用
-
-
-
溶解方式
- Restore with 0.5 mL distilled water.
-
浓度
- 0.4 mg/mL
-
缓冲液
- PBS, pH 7.2 with 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
-
- CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
-
别名
- CD66e / CEACAM5
-
背景
- CEA is a glycoprotein of 180 kDa m.w. It is a normal constituent of the glycocalix of embryonic endodermal epithelium and is produced mainly in the mucosa of the normal colon.Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100
-
基因ID
- 1048
-
NCBI登录号
- NP_004354
-
UniProt
- P06731
抗原
-