CD31 抗体 (Biotin)
Quick Overview for CD31 抗体 (Biotin) (ABIN111925)
抗原
See all CD31 (PECAM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            免疫原
- Leucocytes of patient suffering from LGL-type leukaemia
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                                            亚型
- IgG1
 
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                                            应用备注
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                        Flow cytometry (1/500). 
 Other applications not tested.
 Optimal dilutions are dependent on conditions and should be determined by the user.
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                                            限制
- 仅限研究用
 
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                                            浓度
- 1.0 mg/mL
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                                            缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freezing and thawing.
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                                            储存条件
- 4 °C/-20 °C
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                                            储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
 
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                                            : "Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells."    in: Journal of lipid research, Vol. 49, Issue 5, pp. 1103-12, (2008)         (PubMed).        
 
 
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                                            : "Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells."    in: Journal of lipid research, Vol. 49, Issue 5, pp. 1103-12, (2008)         (PubMed).        
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    - CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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                                            别名
- CD31 / PECAM1
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                                            背景
- CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in rebulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
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                                            基因ID
- 9606
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                                            UniProt
- P16284
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                                            途径
- Regulation of Actin Filament Polymerization
 抗原
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