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Integrin beta 2 抗体 (Activation Site) (FITC)

Name: Integrin beta 2 抗体 (Activation Site) (FITC)
SKU: ABIN111900
Availability: OutOfStock

ITGB2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-148 FITC

产品编号 ABIN111900

发货至: 中国

Datasheet as PDF

抗原 See all Integrin beta 2 (ITGB2) 抗体

Integrin beta 2 (ITGB2)
抗原表位
19

15

8

7

6

6

5

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Activation Site
适用
193

54

45

10

6

4

3

2

2

2

2

2

2

2

1

1
人
宿主
100

89

36

2

1

1
小鼠
Compatible Secondaries
克隆类型
134

90

2
单克隆
标记
103

22

21

16

8

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This Integrin beta 2 antibody is conjugated to FITC
应用范围
132

83

53

45

39

32

29

26

26

26

22

12

9

3

3

3

2

2

1

1
Flow Cytometry (FACS)

特异性

This antibody recognises an epitope on the CD18 Molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognised by MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH .

纯化方法

Affinity chromatography on Protein G

克隆位点

MEM-148

亚型

IgG1

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ITGB2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-48 FITC

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anti-Integrin beta 2 (ITGB2) (AA 701-770) antibody
ITGB2 适用: 人, 大鼠 ELISA, IHC (fro), IHC (p), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.1 mg/mL

缓冲液

Contains 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

Integrin beta 2 (ITGB2)

别名

CD18 / ITGB2 (ITGB2 产品)

背景

CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7

基因ID

3689

NCBI登录号

NP_000202

UniProt

P05107

途径

NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation