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beta Actin 抗体 (N-Term)

This anti-beta Actin antibody is a 兔 多克隆 antibody detecting beta Actin in WB. Suitable for 小鼠, 大鼠 和 猴.
产品编号 ABIN1112710
发货至: 中国

Quick Overview for beta Actin 抗体 (N-Term) (ABIN1112710)

抗原

See all beta Actin (ACTB) 抗体
beta Actin (ACTB) (Actin, beta (ACTB))

适用

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小鼠, 大鼠, 猴

宿主

  • 116
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克隆类型

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多克隆

标记

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This beta Actin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 40
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    N-Term

    特异性

    Detect endogenous level of total beta-Actin protein.

    免疫原

    A synthetic peptide (conjugated to KLH) corresponding to N-terminal residues of human beta-Actin.

    亚型

    IgG
  • 应用备注

    WB (1:2000) Other applications have not been tested. The optimal dilutions should be determined by end user.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    储存条件

    -20 °C

    储存方法

    Store at -20 °C for 1 year. Avoid repeated freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    beta Actin (ACTB) (Actin, beta (ACTB))

    别名

    beta-Actin

    背景

    Beta-actin (gene name ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Karakozova et al. (2006) found that approximately 40% of intracellular beta-actin is arginylated in vivo. In both wildtype and Ate1-null cells beta-actin was stable, suggesting that arginylation does not induce beta-actin degradation. And arginylation of beta-actin apparently represents a critical step in the actin N-terminal processing needed for actin functioning in vivo. 1 Nitric oxide (NO) is a paracrine mediator of vascular and platelet function that is produced in the vasculature by NO synthase-3. And beta-actin plays a critical role in regulating NO formation and signaling in platelets. 2 Beta actin is also usually used as a loading control, for among others, the integrity of cells, protein degradation, in PCR and Western Blotting.

    途径

    Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
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