beta Actin 抗体 (N-Term)
Quick Overview for beta Actin 抗体 (N-Term) (ABIN1112710)
抗原
See all beta Actin (ACTB) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- N-Term
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                                            特异性
- Detect endogenous level of total beta-Actin protein.
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                                            免疫原
- A synthetic peptide (conjugated to KLH) corresponding to N-terminal residues of human beta-Actin.
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                                            亚型
- IgG
 
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                                            应用备注
- WB (1:2000) Other applications have not been tested. The optimal dilutions should be determined by end user.
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            储存液
- Sodium azide, Thimerosal (Merthiolate)
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20 °C for 1 year. Avoid repeated freeze and thaw cycles.
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                                            有效期
- 12 months
 
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    - beta Actin (ACTB) (Actin, beta (ACTB))
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                                            别名
- beta-Actin
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                                            背景
- Beta-actin (gene name ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Karakozova et al. (2006) found that approximately 40% of intracellular beta-actin is arginylated in vivo. In both wildtype and Ate1-null cells beta-actin was stable, suggesting that arginylation does not induce beta-actin degradation. And arginylation of beta-actin apparently represents a critical step in the actin N-terminal processing needed for actin functioning in vivo. 1 Nitric oxide (NO) is a paracrine mediator of vascular and platelet function that is produced in the vasculature by NO synthase-3. And beta-actin plays a critical role in regulating NO formation and signaling in platelets. 2 Beta actin is also usually used as a loading control, for among others, the integrity of cells, protein degradation, in PCR and Western Blotting.
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                                            途径
- Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
 抗原
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