KLKB1 抗体
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北京 101111
Quick Overview for KLKB1 抗体 (ABIN111208)
抗原
See all KLKB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes two variants of Prekallikrein and its activation products Kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). Recognizes Prekallikrein and its activation products in Human, Chimpanzee, Rhesus, and Baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in Human and Rhesus plasmas by approximately 60-80 % and 55 %, respectively. Does not cross-react with tissue Kallikrein
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纯化方法
- Protein G chromatography.
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免疫原
- Purified Human prekallikrein.
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亚型
- IgG1
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anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (Internal Region) antibody
KLKB1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (cleaved), (Internal Region) antibodyKLKB1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 20-300) antibodyKLKB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 503-612) antibodyKLKB1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人 ELISA, IHC, IHC (p), IEP 宿主: 绵羊 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 391-638) antibodyKLKB1 适用: 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) antibodyKLKB1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9F6 unconjugated Recombinant Antibody
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (AA 341-390), (Cleaved-Arg390) antibodyKLKB1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) (Internal Region) antibodyKLKB1 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suitable for use in ELISA and Western blot. Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasmasamples.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.6 mg/mL (OD280 nm)
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缓冲液
- PBS, pH 7.4 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
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背景
- Plasma Kallikrein 1B is a serine proteinase of the S1 family It is secreted by the liver, kidney, adrenal gland and placenta. The zymogen is referred to as prekallikrein (PK) and is activated by Factor XIIa to an active two chain form, plasma kallikrein. In Fletcher syndrome plasma kallikrein is deficient, resulting in a prolonged partial thromboplastin time (PT).Synonyms: Fletcher factor, Plasma kallikrein
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基因ID
- 3818
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NCBI登录号
- NP_000883
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UniProt
- P03952
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途径
- Complement System, Brown Fat Cell Differentiation
抗原
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