TIMD4 抗体
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北京 101111
Quick Overview for TIMD4 抗体 (ABIN1109254)
抗原
See all TIMD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody Kat5-18 recognizes T-cell immunoglobulin and mucin domain containing molecule (TIMD-4, also called TIM-4).
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交叉反应 (详细)
- Species reactivity (tested):Mouse
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纯化方法
- Purified
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免疫原
- Mouse peritoneal cells
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % bovine serum albumin
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
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别名
- TIMD4
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背景
- TIMD-4 is a type I transmembrane protein belonging to the immunoglobulin superfamily, containing one Ig-like V-type (immunoglobulin-like) domain. TIMD-4 is expressed in Mac1+ cells in spleen, lymph nodes and fetal liver. TIMD-4 binds apoptotic cells by recognizing phosphatidylserine via its immunoglobulin domain. TIMD-4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIMD-4 is involved in regulating T-cell proliferation and lymphotoxin signaling. TIMD-4 and TIMD-1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and are also involved in intracellular signaling in which exosomes are involved.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4
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基因ID
- 276891
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NCBI登录号
- NP_848874
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UniProt
- Q6U7R4
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途径
- Cancer Immune Checkpoints
抗原
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