SOCS1 抗体 (C-Term)
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Quick Overview for SOCS1 抗体 (C-Term) (ABIN1109093)
抗原
See all SOCS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects SOCS1 / JAB (C-term). No cross reactivity with other proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Immunogen affinity purified
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1 .Remarks: Sequence is identical to the related mouse and rat sequence.
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibody
SOCS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibodyVerified SOCS1 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibodySOCS1 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66) antibodySOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibodySOCS1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66), (N-Term) antibodySOCS1 适用: 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17347 unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 121-211) antibodySOCS1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibodySOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibodySOCS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibodySOCS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
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别名
- SOCS1
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背景
- Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.Synonyms: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
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基因ID
- 8651
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NCBI登录号
- NP_003736
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UniProt
- O15524
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
抗原
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