PAI1 抗体
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- 抗原 See all PAI1 (SERPINE1) 抗体
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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适用
- 人, 小鼠, 大鼠, 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PAI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat and Rabbit.
- 克隆位点
- MA-33H1F7
- 亚型
- IgG1
- Top Product
- Discover our top product SERPINE1 Primary Antibody
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anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibody
SERPINE1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1D5 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (Internal Region) antibodyVerified SERPINE1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 86-185) antibodySERPINE1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D5 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) antibodySERPINE1 适用: 人, 猴 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 6F3 unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-402) antibodySERPINE1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 141-389) antibodySERPINE1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 1 (SERPINE1) (AA 24-398) antibodySERPINE1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.02 % Sodium Azide, 0.1 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- 别名
- SERPINE1 / PAI1 (SERPINE1 产品)
- 别名
- PAI antibody, PAI-1 antibody, PAI1 antibody, PLANH1 antibody, SERPINE1 antibody, si:ch211-138a11.1 antibody, Planh1 antibody, PAI1A antibody, Pai1 antibody, Pai1aa antibody, Planh antibody, RATPAI1A antibody, serpin family E member 1 antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antibody, serine (or cysteine) peptidase inhibitor, clade E, member 1 antibody, SERPINE1 antibody, serpine1.L antibody, serpine1 antibody, Serpine1 antibody
- 背景
- Plasminogen activator inhibitor type-1 (PAI-1), a member of the serine protease inhibitor (serpin) superfamily is an important protein in the regulation of fibrinolysis. PAI-1 is unique among the serpins because of its functional and conformational flexibility. PAI-1 is the most important physiological inhibitor of both tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA). Increased PAI-1 levels are associated with thrombotic events and is an established risk factor for cardiovascular diseases. The active conformation PAI-1 inhibits its target proteinases by the formation of a stable, inactive complex. Although PAI-1 is synthesized as an active molecule, it converts spontaneously to an inactive, latent form that can be partially reactivated by denaturing agents. In addition, a third conformation reacting as a non-inhibitory substrate towards various target proteinases has been identified.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1
- NCBI登录号
- NM_000602
- UniProt
- P05121
- 途径
- p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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