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S100A8 抗体

S100A8 适用: 人 WB, EIA 宿主: 小鼠 Monoclonal 7C12-4 unconjugated
产品编号 ABIN1108923
发货至: 中国
  • 抗原 See all S100A8 抗体
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    适用
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    宿主
    • 80
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    小鼠
    克隆类型
    • 86
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    单克隆
    标记
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    This S100A8 antibody is un-conjugated
    应用范围
    • 72
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes an epitope on the S100A8 (MRP-8) protein.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    克隆位点
    7C12-4
    亚型
    IgM
    Top Product
    Discover our top product S100A8 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    别名
    S100A8 / Calgranulin-A / MRP8 (S100A8 产品)
    别名
    60B8AG antibody, CAGA antibody, CFAG antibody, CGLA antibody, CP-10 antibody, L1Ag antibody, MA387 antibody, MIF antibody, MRP8 antibody, NIF antibody, P8 antibody, Mrp8 antibody, S100A8 antibody, 60B8Ag antibody, AI323541 antibody, B8Ag antibody, CFAg antibody, Caga antibody, p8 antibody, MRP-8 antibody, S100 calcium binding protein A8 antibody, S100 calcium binding protein A8 (calgranulin A) antibody, S100A8 antibody, S100a8 antibody
    背景
    The calcium-binding, migration inhibitory factor-related proteins, MRP-8 (S100A8) and MRP-14 (S100A9) belong to the S100 protein family. The expression of these proteins is largely confined to the cytosol of neutrophils and monocytes. The complex formation of these proteins is a calcium-dependent process. The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60 % of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. In inflammatory conditions small venueles stain with both anti-S100A8 and S100A9. The staining of the two subunits is always coincident. The S100A8/A9 complex has antibacterial, antifungal and immunomodulating and antiproliferative effects. Besides this it is a potent chemotactic factor for neutrophils.Synonyms: CAGA, CFAG, Calprotectin L1L subunit, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MRP-8, Migration inhibitory factor-related protein 8, S100 calcium-binding protein A8, S100-A8, Urinary stone protein band A
    基因ID
    6279
    NCBI登录号
    NP_002955
    UniProt
    P05109
    途径
    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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